Check whether current application is running over 64-bit OS or not you can check with following way
IsWow64Process function is from the Kernel32 windows library.
you can call it by
Dim blnIs64bit As Boolean
Dim blnSuccess As Boolean = IsWow64Process(Process.GetCurrentProcess().Handle, blnIs64bit)
Defination for IsWow64Process is as below :
<DllImport("kernel32.dll", SetLastError:=True, CallingConvention:=CallingConvention.Winapi)> _
Public Shared Function IsWow64Process(<[In]()> ByVal hProcess As IntPtr, <Out()> ByRef lpSystemInfo As Boolean) As Boolean
End Function
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